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Journal of Dental Research, Vol 56, 716-721, Copyright © 1977 by International & American Associations for Dental Research Online Journals

ARTICLES

Enamel fluoride uptake and retention from intensive APF gel applications in vivo

J. R. Mellberg, C. R. Nicholson, G. J. Franchi, H. R. Englander and G. W. Mosley

Children, in the fifth school grade (mean age 11 years) in a fluoridated water area, self-applied acidulated phosphate-F gel (1.2% F) in custom-fitted mouthpieces on 5, 10, or 25 consecutive school days. Enamel F uptake, penetration, and retention were determined from analysis of 1,257 deciduous teeth exfoliated during and after the applications. F penetrated to 200 micrometer in enamel exposed to 25 applications of the gel and increased approximately 2,600 ppm at a 5 micrometer depth. Concentrations of F declined for approximately eight months after which levels stabilized, resulting in a 1,600 ppm increase of firmly bound F.




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