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Journal of Dental Research, Vol 56, 416-424, Copyright © 1977 by International & American Associations for Dental Research Online Journals

ARTICLES

Collagenolysis by human gingival fibroblast cell lines

G. G. Rose and P. B. Robertson

Human gingival fibroblast cell lines were initiated in flask cultures from four periodontal patients with the diagnoses of periodontitis (two patients), fibromatosis, and Dilantin hyperplasia. The collagenolytic propensity of these fibroblasts cultivated on collagen-coated cover slips and the inhibitory effect of serum were evaluated by direct microscopic observations.




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