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Journal of Dental Research, Vol 56, 254-265, Copyright © 1977 by International & American Associations for Dental Research Online Journals

ARTICLES

Reduction of dental decay in rampant caries individuals following short-term kanamycin treatment

W. J. Loesche, D. R. Bradbury and M. P. Woolfolk

A week of kanamycin gel treatment before and after the placement of dental restorations, compared to a placebo gel treatment, significantly reduced the levels of cultivable bacteria, S mutans and S sanguis, in the plaque samples collected immediately after the completion of the gel treatments, and was associated with a 46% reduction in new carious surfaces in the 14- to 37-month period following the gel treatment.




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Journal of Dental Research ® Critical Reviews (1990-2004)
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