Journal of Dental Research, Vol 56, 1369-1375, Copyright © 1977 by International & American Associations for Dental Research Online Journals
The seeded growth of calcium phosphates on dentin and predentin
M. B. Tomson, B. Tomazic, G. H. Nancollas, W. Miller and M. Everett
The in vitro mineralization of predentin (PD) and of the organic component
of dentin (OD) has been studied in a supersaturated solution of calcium
phosphate at 37 C and pH=7.4 at total calcium and phosphate concentrations
close to those in vivo. The mineralization of OD can be divided into at
least three periods based upon the morphology and the specific surface area
of the mineral phase formed. Dissolution of the newly precipitated mineral
on OD revealed a stoichiometry close to that for octacalcium phosphate. In
contrast, PD was ineffective as a crystal nucleator. The mineralization of
the inorganic component of dentin (ID) and whole dentin (D) has also been
examined.
