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Journal of Dental Research, Vol 56, 1255-1259, Copyright © 1977 by International & American Associations for Dental Research Online Journals

ARTICLES

Influence of various inhibitors on alkaline phosphatase in calicifying hamster molars, employing paranitrophenyl phosphate as substrate

J. H. Woltgens

In mineralizing hamster molars, the influence of several inhibitors on p-NPP-ase has been demonstrated, and compared with their effect on PPi-ase, known to belong to the same enzyme. Whereas the latter activity is much more physiological, p-NPP is a better substrate to distinguish between the effects of bivalent cations on the enzyme or the substrate.




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