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Journal of Dental Research, Vol 55, 1092-1096, Copyright © 1976 by International & American Associations for Dental Research Online Journals

ARTICLES

Cariostatic activity of calcium glycerophosphate in hamsters: topical vs dietary administration

R. S. Pianotti, J. D. Ambrozaitis and T. F. McNamara

Two experiments were conducted to determine if calcium glycerophosphate administered continuously in a diet or intermittently as a single daily topical application to teeth had an anticaries potential in young hamsters that were fed a cariogenic diet. The hamsters were inoculated with a caries-conductive streptococcal strain. Within the 60-day experimental period, results of these evaluations indicated calcium glycerophosphate significantly reduces caries when fed in the diet at levels of 1% and higher, and significantly reduces caries when applied topically at levels of 2% and higher. There were no observable differences in plaque formation among treatments.




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