Journal of Dental Research, Vol 55, 848-853, Copyright © 1976 by International & American Associations for Dental Research Online Journals
Mandibular condylectomy in the guinea pig: quantitative triple fluorochrome study
N. N. Soni and R. B. Malloy
Different-colored fluorochromes were administered sequentially to guinea
pigs and the rate of bone formation measured in their condylectomized
control contralateral hemimandibles. The values for labeled bone for
condylectomized hemimandibles were lower than for the control contralateral
hemimandibles of the same guinea pig. The differences in values of
condylectomized and control contralateral sides for DCTC- and total surface
area-labeled bone were statistically significant, but were not
statistically significant for DCAF- and hematoporphyrin-labeled bone. There
was partial regeneration of the condylar process. Although the
condylectomized area was nearly normal in shape, its size and proportions
were different from those of the contralateral hemimandibles that were not
operated on. The greatest differences were noted in the length, height, and
the distances measured between the inferior alveolar foramen and the mental
foramen and the posterior border of the condyle.
