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Journal of Dental Research, Vol 55, 476-480, Copyright © 1976 by International & American Associations for Dental Research Online Journals

ARTICLES

Selection of an experimental unit in rat caries studies

W. W. Briner

In two separate experiments, none of the 14 subunits examined consistently ranked dentifrices similarly to the ranking obtained when the individual rat was used as the experimental unit. Arbitrarily dividing the rat into subunits and then comparing results among these subunits may lead to false conclusions since the rankings using subunits vary within each experiment and from experiment to experiment.




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