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J Dent Res 54(6): 1200-1206, 1975
© 1975 International and American Associations for Dental Research
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Effects of Anti-Inflammatory Steroids on Mouse Embryonic Movements During Palatal Development

BRUCE E. WALKER 1 and JOAN QUARLES 1

1 Department of Anatomy, Michigan State University, East Lansing, Michigan 48824, USA

The frequency of spontaneous embryonic muscular movements was recorded for embryos from mice treated with cortisone or triamcinolone. Movement was significantly reduced in A/J strain mouse embryos exposed to these anti-innflammatory agents. Cleft palates induced by the drugs may originate from failure of the embryonic tongue to be withdrawn from between the palatine shelves.

Submitted on August 29, 1974
Accepted on June 27, 1975






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