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J Dent Res 54(6): 1180-1182, 1975
© 1975 International and American Associations for Dental Research

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Lingual Ascorbic Acid Test: Poor Correlation with Blood and Tissue Levels of Ascorbic Acid in Guinea Pigs

LILA INOUYE 1, SANFORD A. MILLER 1, and MICHAEL C. ALFANO 1

1 Oral Science Laboratories, Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA

The lingual ascorbic acid test, based on the reduction and decolorization of the blue dye, 2,6-dichloroindophenol sodium, was evaluated in a group of guinea pigs conditioned to have a wide range of ascorbic acid levels in the tissues. This test did not correlate well with ascorbic acid levels in either blood or tissue.

Submitted on January 20, 1975
Accepted on June 26, 1975







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