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J Dent Res 54(5): 968-971, 1975
© 1975 International and American Associations for Dental Research
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Quantitative Studies of In Vitro Inhibition of Streptococcus mutans Plaque Formation by Organic Amines

G. E. BASS 1, E. O. DILLINGHAM 1, and LARRY J. POWERS 1

1 Department of Molecular Biology, University of Tennessee Center for the Health Sciences, Memphis, Tennessee 38163, USA

The abilities of five, long-chain aliphatic monamines to inhibit the deposition of plaque formed by Streptococcus mutans on stainless-steel wires were determined. The compounds along with their relative inhibitory potencies that were studied are N-methyltetradecylamine, hexadecylamine, dodecylamine, N-ethyldodecylamine, and octylamine. Activities are compared with critical micelle concentrations, partition coefficients, and quantum mechanical charges on the amine nitrogens.

Submitted on September 6, 1974
Accepted on March 4, 1975






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