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J Dent Res 54(4): 822-828, 1975
© 1975 International and American Associations for Dental Research
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Dose-Dependent Ultrastructural Changes Induced by Tetracycline in Developing Dental Tissues of the Rat

B. J. KRUGER 1

1 Oral Biology, Physiology Building, University of Queensland, St. Lucia, Australia 4067

Tetracycline was administered to rats in varying doses in order to study the likelihood of ultrastructural alterations to ameloblasts and to study odontoblasts and dentin as well. The changes caused by tetracycline to the mineralization of dentin and the ultrastructural changes to the odontoblasts and ameloblasts increased with larger doses.

Submitted on June 18, 1974
Accepted on November 20, 1974






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