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J Dent Res 54(3): 615-625, 1975
© 1975 International and American Associations for Dental Research
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Some Toxicological Aspects of Stannous Fluoride After Ingestion as a Clear, Precipitatefree Solution Compared to Sodium Fluoride

JAMES K. J. LIM 1, GUY K. JENSEN 1, and ORDIE H. KING JR 1

1 School of Pharmacy and School of Dentistry, West Virginia University Medical Center, Morgantown, West Virginia 26506, USA

Weanling rats were administered 20, 380, and 20,000 ppm F as clear precipitatefree SnF2 solutions. Equivalent ppm F as NaF solution was similarly administered for comparison. The rats were autopsied at the end of the study for histological examination of kidney, liver, and incisors. The pathognomonic manifestations were correlated with the plasma F levels.

Submitted on February 21, 1974
Accepted on August 29, 1974






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