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1 Department of Oral Medicine, School of Dentistry, and Department of Physiology, School of Medicine, Loma Linda University, Loma Linda, California 92354, USA
Weanling rats fed a cariogenic diet supplemented with carbamyl phosphate, in combination with egg shell meal and trace elements, showed a striking reduction in the incidence of caries. The cariostatic efficacy of carbamyl phosphate is significant because it stimulates fluid movement within odontoblasts via the hypothalamic-parotid gland endocrine axis.
Submitted on April 8, 1974
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