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J Dent Res 54(1): 97-103, 1975
© 1975 International and American Associations for Dental Research
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Postdevelopmental Effects of Boron, Fluoride, and Their Combination on Dental Caries Activity in the Rat

F. T. Y. LIU 1

1 Department of Physiology, University of Missouri-Kansas City School of Dentistry, Kansas City, Missouri 64108 USA

Drinking water of rats aged 21 days was supplemented with 1, 10, 30, 50, 100, or 283 ppm of boron or 10 or 25 ppm of fluoride individually or in combination. All rats were fed a cariogenic diet. Boron did not reduce dental caries activity in erupted molars after eight weeks. When given in combination, it partially antagonized the cariostatic effect of fluoride.

Submitted on December 19, 1973
Accepted on June 18, 1974






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