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J Dent Res 54(1): 16-19, 1975
© 1975 International and American Associations for Dental Research
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Hypodontia: A Polygenic Trait—A Family Study Among Israeli Jews

AUBREY CHOSACK 1, ELIECER EIDELMAN 1, and TIRZA COHEN 1

1 Departments of Pedodontics and Human Genetics, Faculty of Medicine, Hebrew University-Hadassah Medcial Center, Jerusalem, Israel

A high prevalence of hypodontia was detected among 820 first degree relatives of 305 probands and there was an increased risk if a second family member was affected. Hypodontia is a common trait in the population, and a deviation from normal sex ratio was observed in those affected. These results suggest a polygenic mode of inheritance.

Submitted on February 8, 1974
Accepted on August 12, 1974






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