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J Dent Res 53(3): 609-622, 1974
© 1974 International and American Associations for Dental Research

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Comparative Assessment of the Cell Proliferative Activities of Injured Parodontal Tissues in Aging Mice

E. A. TONNA 1 and S. S. STAHL 1

1 Institute for Dental Research, Brookdale Dental Center of New York University, New York, New York 10010, USA

Little effect was noted on the labeling indexes of the gingival epithelium in aging mice after gingival excision. However, significantly diminished labeling indexes, shifted peak activities to later time periods, and delayed tissue regeneration were observed in associated connective tissues. The effects of aging were most pronounced on the connective tissue compartments that retained their cell proliferative potential despite aging.

Submitted on March 30, 1973







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