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J Dent Res 53(3): 588-591, 1974
© 1974 International and American Associations for Dental Research
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Diphenylhydantoin Sodium (Dilantin) as a Caries Retarder

SHELDON ROVIN 1, WILLIAM R. SABES 1, LEWIS R. EVERSOLE 1, and HELMUT A. GORDON 1

1 Department of Oral Pathology, University of Kentucky, College of Dentistry, Lexington, Kentucky 40506 USA

Rats that had their mandibular first molars silk-ligated and that were fed chow with diphenylhydantoin sodium (Dilantin) developed less caries than rats that were not fed Dilantin. The retarding effect of Dilantin was enhanced by the cleanliness of the environment in which the animals lived.

Submitted on June 5, 1973






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