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1 Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
A sensitive and quantitative assay to measure the early calcium loss from surface enamel exposed to organic acids and metabolic products of cariogenic bacteria was designed. It will be useful to show the effects of metabolic products from cariogenic organisms on the surface of enamel and the effectiveness of dental therapeutic agents before animal studies.
Submitted on January 8, 1973
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