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J Dent Res 53(2): 375-378, 1974
© 1974 International and American Associations for Dental Research
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Effects of Proteolytic Enzymes on Posteruptive Maturation, Remineralization, and the Caries-Preventive Effects of Fluoride in Rats

W. W. BRINER 1, C. C. HENDERSON 1, and J. S. WIDDER 1

1 The Procter & Gamble Company Division of Dental Research, Cincinnati, Ohio 45224, USA

The object of these studies was to determine the effect of topically applied bacterial proteases on posteruptive maturation of rat molars, on remineralization of incipient lesions in rats, and on the caries-preventive effect of fluoride in rats as evidenced by changes in hypomineralized areas in molars. Our findings showed that the topically applied proteases had no effect on the foregoing phenomena.

Submitted on May 7, 1973






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