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J Dent Res 53(1): 115-120, 1974
© 1974 International and American Associations for Dental Research
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Effect of a Topically Applied 3% Vancomycin Gel on Streptococcus mutans on Different Tooth Surfaces

HAROLD V. JORDAN and PAUL F. DE PAOLA

A 3% vancomycin gel was applied for ten minutes to the teeth of 10- to 12-year-old children using custom-fitted trays. Treatment was once a day for five consecutive days. Significant suppression of Streptococcus mutans was found in sound and carious fissures one week after treatment, with a decline in the oral hygiene index. Response to treatment was the same in subjects with and without large, open, carious lesions.

Submitted on June 6, 1973




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