Effects of Fluorides in the In Vitro Plaque Model System from Human Salivary Sediment

¹ Menley & James Laboratories, Ltd., Philadelphia, Pennsylvania 19101, USA

Artificial plaque from human saliva produces glycolytic action after three to four hours incubation at 37 C. When 6 to 8 ppm F from aminefluorides is present, such effects are absent. Under the same conditions, up to 100 ppm F from sodium fluoride and monofluorophosphate are inactive; stannous fluoride is active at 50 ppm F, but not at 10 ppm F. A marketed preparation of a gel that contains aminefluoride is active at 80 ppm F, whereas an inorganic fluoride gel is active only at 1,250 ppm F.