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J Dent Res 52(5): 1097-1109, 1973
© 1973 International and American Associations for Dental Research
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Mechanism for the Retardation of the Acid Dissolution Rate of Hydroxyapatite by Strontium

MAHENDRA G. DEDHIYA 1, FUDAH YOUNG 1, and WILLIAM I. HIGUCHI 1

1 College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48104, USA

Dissolution rates and apparent solubilities for synthetic hydroxyapatite in acetate buffers containing phosphate and strontium ions in the range of 10-3 to 10-2 M were determined under various pH and buffer conditions. Critical examination of the role of strontium with a physical model suggests that a calcium-strontium apatite surface complex may govern the driving force of the dissolution reaction.

Submitted on November 30, 1972






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