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J Dent Res 52(5): 1087-1091, 1973
© 1973 International and American Associations for Dental Research

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Induced Calcification in the Subdermal Tissues of the Rat

WILLIAM H. BINNIE 1 and DAVID F. MITCHELL 1

1 Department of Oral Diagnosis/Oral Medicine, Indiana University School of Dentistry, Indianapolis, Indiana 46202, USA

Subdermal implants of calcium hydroxide, magnesium hydroxide, plaster of Paris, and a control material were made in rats. A tetracycline and a chloro-s-triazine dye were given at various intervals to some rats. Histochemical and fluorescence studies showed an amorphous, lamellar, noncellular, mineralized tissue in the capsules surrounding the inorganic implants.

Submitted on November 27, 1972







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