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J Dent Res 52(4): 753-757, 1973
© 1973 International and American Associations for Dental Research
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Effect of the Contraceptive Steroids Norethynodrel and Mestranol on Dental Caries Activity in Young Adult Female Rats

F. T. Y. LIU 1 and H. S. LIN 1

1 Department of Physiology, School of Dentistry, University of Missouri-Kansas City, Missouri 64108, USA

Norethynodrel and mestranol in a ratio identical to that used for contraception were injected subcutaneously daily for five weeks into young adult female rats. These rats were fed with a purified caries test diet. The carious lesions of the treated rats increased proportionately with increased doses of the agents.

Submitted on June 13, 1972






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