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J Dent Res 52(4): 658-667, 1973
© 1973 International and American Associations for Dental Research
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Effects of Dextranase from Spicaria violaceae (IFO 6120) on the Polysaccharides Produced by Oral Streptococci and on Human Dental Plaque

YOJI MURAYAMA 1, HAJIME WADA 1, HIRO-O HAYASHI 1, TAKESHI UCHIDA 1, ICHIRO YOKOMIZO 1, and SHIGEYUKI HAMADA 1

1 Department of Endodontics and Periodontics and Department of Oral Microbiology, Osaka University Dental School, Osaka, Japan

Dextranase was prepared from Spicaria violaceae. The in vitro effect of the dextranase on the various polysaccharides produced by oral streptococci was studied. In vivo studies revealed that the dextranase was capable of preventing dental plaque deposition in man.

Submitted on April 24, 1972






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