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J Dent Res 52(3): 472-475, 1973
© 1973 International and American Associations for Dental Research

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Improvement in Abrasive Biopsy Sampling of Tooth Enamel

J. R. MELLBERG 1, C. R. NICHOLSON 1, H. R. ENGLANDER 1, and H. J. KEENE 1

1 Davies Rose Hoyt Pharmaceutical Division, The Kendall Company Research Center, Barrington, Illinois, 60010, USA; National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland; and Naval Dental Research Institute, Great Lakes, Illinois

The abrasive biopsy technique for removal of enamel in vivo was modified by controlling the biopsy area, polishing speed, and pressure. These modifications resulted in greater uniformity of samples obtained by a single operator, as well as between different operators. A mean depth of 2.5 µm was obtained within the standardized area of the controlled biopsies.

Submitted on March 3, 1972







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