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J Dent Res 52(2): 371-376, 1973
© 1973 International and American Associations for Dental Research
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Lysis of Certain Organisms by the Synergistic Action of Complement and Lysozyme

H. BLADEN 1, G. HAGEAGE 1, R. HARR 1, and F. POLLOCK 1

1 Laboratory of Biological Structure, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20014, USA

A study was made to determine the effect of lysozyme on certain oral organisms after exposure to guinea pig complement (C'). No effect was observed on gram-positive streptococci or strains of Actinomyces whether pretreated with C' or not. Strains of Veillonella, a gram-negative organism, were partially lysed by the synergistic action of C' and lysozyme. This reaction is described in detail.

Submitted on July 27, 1972






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