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J Dent Res 52(2): 206-210, 1973
© 1973 International and American Associations for Dental Research
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Further Studies Concerning the Placental Transfer of Fluoride in the Rat

SIMON KATZ 1 and GEORGE K. STOOKEY 1

1 Oral Health Research Institute, Indiana University-Purdue University at Indianapolis, Indianapolis, Indiana 46202, USA

Female rats were given 25 ppm fluoride as various fluoride compounds during gestation or 25 ppm fluoride as NaF during gestation and a pregestational period. Offspring were killed at birth and analyzed for fluoride. Fluoride compounds given during gestation resulted in comparable amounts of fluoride in the offspring, but a greater amount was observed in pups whose mothers received ZrOGeF6. Pregestational fluoride exposure increased the amount of transplacental fluoride transfer.

Submitted on February 11, 1971






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