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J Dent Res 52(1): 23-25, 1973
© 1973 International and American Associations for Dental Research

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Studies in the Design and Analysis of Dental Experiments: 14. Replicate Latin Squares

ANDRE A. O. VARMA 1, NEAL W. CHILTON 1, and AUSTIN H. KUTSCHER 1

1 School of Public Health of the Faculty of Medicine and the School of Dental and Oral Surgery, Columbia University, New York, New York 10032, USA

Three doses of a lozenge were administered in two locations to 30 individuals (including six smokers) assigned to five 6 by 6 Latin squares. The two locations, the corresponding dose-response curves, and the effect of smoking were compared. No significant differences in the dissolution times were found.

Submitted on October 8, 1971







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