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J Dent Res 52(1): 111-115, 1973
© 1973 International and American Associations for Dental Research
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Plaque Acid Production in Hamsters Pretreated with Fluoride

DOROTHEA B. FITZGERALD 1 and ROBERT J. FITZGERALD 1

1 Institute of Oral Biology, University of Miami School of Medicine, Miami, Florida 33152, USA and Dental Research Unit, VA Hospital, Miami, Florida

Plaque acid production in hamsters pretreated with fluoride did not differ from that in untreated control hamsters, although sufficient fluoride was present in the teeth of the treated hamsters to protect against a severe cariogenic challenge. The results indicate that enamel-bound fluoride does not significantly influence carbohydrate metabolism of microbial plaques.

Submitted on February 22, 1972






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