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J Dent Res 51(6): 1651-1657, 1972
© 1972 International and American Associations for Dental Research
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Preliminary Study of Inhibitory Effects of Tetracyclines on Membranous Bone Growth in Rhesus Monkeys

PETER K.-J. YEN 1 and JAMES H. SHAW 1

1 Harvard School of Dental Medicine, Boston, Massachusetts 02115, USA

Various doses and forms of tetracycline were administered to young monkeys that received multiple injections of lead acetate as a vital marker of the calcification sites. The effects of these tetracyclines on membranous bone growth were assessed histologically; retarded bone growth occurred under some conditions.

Submitted on December 27, 1971






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