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J Dent Res 51(6): 1594-1595, 1972
© 1972 International and American Associations for Dental Research
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Aphthous Ulceration: The Antinuclear Factor

M. ADDY 1 and A. E. DOLBY 1

1 Dental School, The Welsh National School of Medicine, University of Wales Dental School, Heath, Cardiff, Wales, United Kingdom

The incidence of the antinuclear factor in serum of patients with Mikulicz's recurrent oral aphthae (MROA) was compared with that in control serum. The absence of any difference between the two groups suggests that MROA is not an autoimmune disease arising from a central immunologic fault, but could be a local immune response against an antigenically altered mucosa.

Submitted on August 23, 1971






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