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J Dent Res 51(5): 1426-1430, 1972
© 1972 International and American Associations for Dental Research
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Differential Binding of 14C-Cortisone in Fetal, Placental, and Maternal Liver Tissue in A/Jax and C57BL Mice

THOMAS A. REMINGA 1 and JAMES K. AVERY 1

1 Department of Oral Biology, University of Michigan Dental School, Ann Arbor, Michigan 48104, USA

When 14C-cortisone was given to pregnant A/Jax and C57BL mice, the concentration of radioactivity firmly bound to fetal tissue was significantly higher in A/Jax mice than in C57BL mice. Differences in the binding of cortisone to tissue proteins may explain the differential incidences of cleft palate in A/Jax and C57BL mice.

Submitted on July 26, 1971






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