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J Dent Res 51(5): 1375-1381, 1972
© 1972 International and American Associations for Dental Research
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Patterns of Dental Caries in Osborne-Mendel and NIH Black Rats in Relation to Length of the Caries Test Period

RACHEL H. LARSON 1 and CAROL S. ZICKUS 1

1 Disease Prevention and Therapeutics Branch, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland 20014, USA

Both Osborne-Mendel and NIH Black rats developed carious lesions on the smooth surfaces and in the sulci during the first week on an intensive caries-test challenge. The number and size of lesions continued to increase throughout a ten week experiment. Progression on different surfaces varied with the strain, but final levels were not significantly different.

Submitted on June 21, 1971






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