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J Dent Res 51(4): 1055-1061, 1972
© 1972 International and American Associations for Dental Research
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14C-Eugenol: I. Synthesis, Polymerization, and Use

JACOB E. WEINBERG 1, JOSEPH L. RABINOWITZ 1, MURRAY ZANGER 1, and ALFONSO R. GENNARO 1

1 Veterans Administration Hospital and Center for Oral Health Research, University of Pennsylvania and Philadelphia College of Pharmacy and Science, Philadelphia, Pennsylvania 19104, USA

The mixture of eugenol and zinc oxide resulted in a lignin-like polymer; this was verified by spectroscopy. 14C-eugenol with high specific activity was synthesized and administered intraperitoneally to rats. 14Ceugenol was subsequently found in all tissues. Chromatography was used for separation and quantitation of this compound.

Submitted on June 14, 1971






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