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J Dent Res 51(4): 1010-1014, 1972
© 1972 International and American Associations for Dental Research
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Lack of Difference in Sex Ratio of Mice with Cortisone-Induced Cleft Palate

HANNELORE T. LOEVY 1

1 Department of Pharmacognosy and Pharmacology, College of Pharmacy, University of Illinois, Chicago, Illinois 60612, USA

Cortisone injected into pregnant CD1 and Strong A mice increased the number of resorption sites but had no statistically significant effect on the sex ratio of the surviving fetuses. With one exception, no difference between sexes in incidence of cleft palate was demonstrated, which suggests that cortisone in the dose used did not induce cleft palate through a sexdependent mechanism.

Submitted on May 26, 1971






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