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J Dent Res 51(3): 800-802, 1972
© 1972 International and American Associations for Dental Research
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Desorption of Salivary Proteins from Hydroxyapatite by Phytic Acid and Glycerophosphate and the Plaque-Inhibiting Effect of the Two Compounds In Vivo

HAKON NORDBÖ 1 and GUNNAR RÖLLA 1

1 Department of Physiology and Biochemistry and Department of Operative Dentistry, Dental Faculty, University of Oslo, Oslo, Norway

The capacity of phytic acid and glycerophosphate to desorb salivary proteins from hydroxyapatite was studied in vitro. Phytic acid had a high capacity for desorption; the capacity of glycerophosphate was considerably lower. In vivo experiments showed that both substances were capable of reducing plaque formation; phytic acid had a greater effect. The results may offer an explanation of the cariostatic effect of these substances.

Submitted on April 28, 1971






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