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J Dent Res 50(5): 1301-1306, 1971
© 1971 International and American Associations for Dental Research
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Collagenolysis in Cultured Tissue: II. Role of Mast Cells

A. CECIL TAYLOR 1

1 The University of Texas Dental Science Institute at Houston, Houston, Texas 77025, USA

Lysis of collagen fibers in mesenteries cultured with explants of gingival tissue occurred around degranulating mast cells and their dispersed granules. The mast cell effect was not destroyed by heating the mesentery and was augmented by heparin and vitamin A. Mast cells may function in the control of tissue collagen breakdown through release of an enzyme activator.

Submitted on September 16, 1971






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