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J Dent Res 50(3): 542-550, 1971
© 1971 International and American Associations for Dental Research
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Adsorption of Salivary Proteins by Hydroxyapatite: Relations Between the Effects of Calcium Ions, Hydrogen Ions, Temperature, and Exposure Time

CHARLES MC GAUGHEY 1 and ELLERY C. STOWELL 1

1 Oral Diseases Research Laboratory, Veterans Administration Hospital, Long Beach, California 90801, USA and Department of Biochemistry, School of Medicine, University of Southern California, Los Angeles, California

Calcium ions enhanced the adsorption of salivary proteins by hydroxyapatite. Calcium probably acted in the protein-bound form by promoting the aggregation of proteins. Concentrations of calcium far below physiologic levels exerted maximal effects. Lowering the pH to 5 increased protein adsorption but abolished the effect of calcium. Relevance to the in vivo situation was examined.

Submitted on February 19, 1970






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