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J Dent Res 50(2): 460-465, 1971
© 1971 International and American Associations for Dental Research
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Bone Loss and Caries in Rats Infected with Human Streptococci

LUIS F. DUANY 1, DORAN D. ZINNER 1, and JEROME J. LANDY 1

1 University of Miami, Institute of Oral Biology, Coral Gables, Florida 33136, USA and the Veterans Administration Hospital, Miami, Florida

Gnotobiotic rats infected orally with various human cariogenic Streptococcus mutans strains or a Streptococcus salivarius strain exhibited greater alveolar loss of bone than control rats. The same strains also showed considerable differences in their cariogenic activity. There was a positive correlation between the extent of bone loss and carious surfaces.

Submitted on May 18, 1970






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