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J Dent Res 50(2): 388-392, 1971
© 1971 International and American Associations for Dental Research
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Altered Staining Reaction of Connective Tissues in 53 Submucous Fibrosis Patients

JAMES E. HAMNER 1, FALl S. MEHTA 1, JENS J. PINDBORG 1, and D. K. DAFTARY 1

1 United States Public Health Service, National Institutes of Health, National Institute of Dental Research, Southwest Foundation for Research and Education, San Antonio, Texas 78228, USA; Basic Dental Research Unit Tata Institute of Fundamental Research, Bombay, India; and Department of Oral Pathology, Royal Dental College, Copenhagen, Denmark

Fifty-four oral biopsies were performed on 53 submucous fibrosis patients among 50,915 rural villagers in the Indian states of Kerala, Gujarat, Bihar, and Andhra Pradesh. Histologic sections revealed a definite alteration in the tinctorial quality of the connective tissues when stained by the Rinehart and van Gieson methods. The connective tissues in submucous fibrosis patients tended to be amorphous and nonbundular, in contrast to that seen in the normal controls.

Submitted on March 19, 1970






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