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J Dent Res 49(6): 1509-1512, 1970
© 1970 International and American Associations for Dental Research

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Demineralization of Bone by Phosphoprotein Phosphatase

STEPHEN N. KREITZMAN 1 and MICHAEL E. FRITZ 1

1 Department of Dental Research and Department of Periodontology, School of Dentistry, Emory University, Atlanta, Georgia 30322, USA

Because of recent observations of the demineralization of enamel by phosphoprotein phosphatase, an experiment was designed to test this enzyme on bone. Decided destruction was evident in bone fragments that were incubated with phosphoprotein phosphatase buffered to pH 5.8 with 0.1 M acetate for periods of up to 15 hours.

Submitted on December 19, 1969







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