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1 College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48104 and School of Dentistry, University of Alabama Medical Center, Birmingham, Alabama 35233
A physical model describing the interrelationships of demineralization, remineralization, plaque thickness, glucose levels, and plaque enzymatic activity was presented. Selection of constants and variations of the parameters were kept in the range of possible in vivo situations. The results of calculations were discussed and correlated with the results of in vivo studies.
Submitted on July 22, 1968
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