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1 Department of Preventive Dentistry, Osaka University Dental School, Osaka; Department of Preventive Dentistry, Hiroshima University School of Dentistry, Hiroshima; and Department of Pathology, Institute for the Deaf, Tokyo Medical and Dental University, Tokyo, Japan
Severe osteoporosis and some myelofibrosis of the alveolar bone developed in rats fed a citrate diet. The administration of coenzyme Q7 alleviated these histopathologic effects. It was also demonstrated that hypercitricemia with hypercalcemia found in the citrated rats were significantly restored to normal levels by coenzyme Q7 administration.
Submitted on March 10, 1969
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