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J Dent Res 48(6): 1219-1223, 1969
© 1969 International and American Associations for Dental Research
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Autoradiographic Demonstration of DNA Synthesis in Selected Epithelial Tissues in Male Rats

MARSHALL C. ENGLAND JR. 1 and GEORGE W. BURKE JR. 1

1 School of Dentistry Medical College of Virginia, Health Sciences Division, Virginia Commonwealth University, Richmond, Virginia 23219

Eleven white male rats received intravenous injections of thymidine -3H at a dose rate of I µc/gm body weight. The rats were killed at four-hour intervals over a 24-hour period Epithelial specimens from the hard and soft palate, cheek, skin, and tail were subjected to autoradiography. The results confirm prior data from liquid scintillation studies, which showed a maximal DNA synthesis at 4:30 to 8:45 AM and minimal synthesis at 3:40 to 8:30 PM.

Submitted on December 10, 1968






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