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J Dent Res 48(5): 863-871, 1969
© 1969 International and American Associations for Dental Research
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Effect of Ascorbic Acid on Guinea Pig Skin Collagen Synthesis: I. Total Collagen

VIRGINIA RICHMOND 1 and E. L. R. STOKSTAD 1

1 Department of Nutritional Sciences, University of California, Berkeley, California 94720

A deficiency of ascorbic acid caused a decreased uptake of 3H-proline into guinea pig skin collagen and a further decrease in the HO-proline formation; inanition from pairfeeding was not a contributing factor. An anemia developed in the completely deficient animals which was prevented with low levels of ascorbic acid in another group.

Submitted on May 6, 1968




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K. K. Parsons, N. Maeda, M. Yamauchi, A. J. Banes, and B. H. Koller
Ascorbic acid-independent synthesis of collagen in mice
Am J Physiol Endocrinol Metab, June 1, 2006; 290(6): E1131 - E1139.
[Abstract] [Full Text] [PDF]


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