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J Dent Res 48(5): 702-708, 1969
© 1969 International and American Associations for Dental Research
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Squamous Carcinoma of the Lip: A Study of the Interface Between Neoplastic Epithelium and the Underlying Mesenchyma

J. HAROLD JONES 1 and J. I. COYLE 1

1 Departments of Pathology and Dental Surgery, The Queen's University, Belfast, Northern Ireland

In a study of 50 squamous carcinomas of the lower lip, 25 metastasized and 25 were successfully treated by simple resection. Lack of differentiation, a poor lymphocytic response and, in particular, the formation of a loose, alcian blue and Hale positive fibroblastic stroma were unfavorable prognostic signs.






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