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J Dent Res 48(5): 646-651, 1969
© 1969 International and American Associations for Dental Research
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The Origin of Collagenase in Periodontal Tissues of Man

HAROLD M. FULLMER 1, WILLIAM A. GIBSON 1, GERALD S. LAZARUS 1, HOWARD A. BLADEN 1, and KAREN A. WHEDON 1

1 Department of Health, Education, and Welfare, National Institutes of Health, Bethesda, Maryland 20014

Collagenase is produced by both epithelial and connective tissue cells of the human gingiva. Collagenase action was shown through viscometry, acrylamide gel electrophoresis, and electron microscopy. Collagen is cleaved into one-quarter and three-quarter pieces by collagenase derived from human gingiva.




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I. Rubinstein, X.-P. Gao, S. Pakhlevaniants, and D. Oda
Smokeless tobacco-exposed oral keratinocytes increase macromolecular efflux from the in situ oral mucosa
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[Abstract] [Full Text] [PDF]


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