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J Dent Res 48(4): 568-572, 1969
© 1969 International and American Associations for Dental Research
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Study of Closure of the Embryonic Rat Palate In Vitro with the Effects of Certain Chemicals

J. F. THOMPSON 1 and M. R. SCHWEISTHAL 1

1 Department of Anatomy, Medical College of Virginia, Health Sciences Division, Virginia Commonwealth University, Richmond, Virginia 23219

In organ cultures of rat-palatal processes from 15-day-old embryos, addition of vitamin A or vitamin A with cortisone to the culture medium caused nonfusion and epithelial disruption. Cortisone alone did not show a teratogenic effect; nor did it exaggerate the effect of vitamin A.

Submitted on November 12, 1968






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